PENGARUH PEMBERIAN EKSTRAK DAGING BUAH PUPIA (Momordica cochinchinensis) TERHADAP KADAR HEMOGLOBIN MENCIT (Mus musculus)

Abstract

The Effect of Ageratum conyzoides L Herbs Methanol Extract AgainstMus musculus) This study aims to determine the effect of Bandotan Herbaceous (Ageratum conyzoides L) Methanol Extract on Histology of Mice (Mus musculus) Histology. This type of research is an experimental research Laboratory of Mice which used 12 tails, were divided into 4 groups. Each group consists of 3 mice. three groups were given a suspension of Bandotan Leaf Methanol Extract at a dose of 12 mg / gBB, 24 mg / gBB, 48 mg / gBB, and one group as a control was given a 1% w / v Na-CMC suspension. Giving bandotan extract was carried out for 14 days and day 15 was performed surgery of mice test animals and then the results of preparations were seen. Based on the results of research on the influence of Methanol Extract of BandotanHerba (Ageratum conyzoides L) Against the Histology Picture of Mice Liver (Mus musculus) it can be concluded that Methanol Extract of Bandotan Herba (Ageratum conyzoides L) treatment group at a dose of 12 mg / gBB and 24 mg / gBB and 48 mg / gBB showed the presence of necrosis, fat degeneration, and inflammation. While the negative control (-) in the administration of NaCMC suffered damage to fat degeneration in the liver

Pengaruh Pemberian Ekstrak Metanol Herba Bandotan (Ageratu  conyzoides L) Terhadap Gambaran Histologi Hati Mencit (Mus musculus) Penelitian ini bertujuan untuk mengetahui Pengaruh Ekstrak Metanol Herba Bandotan (Ageratum conyzoides L) Terhadap Gambaran Histologi Hati Mencit (Mus musculus).Desain penelitian ini adalah penelitian eksperimental Laboratorium.Mencit yang digunakan sebanyak 12 ekor, di bagi menjadi 4 kelompok.Tiap kelompok terdiri dari 3 mencit. Tiga kelompok diberi suspense Ekstrak Metanol Daun Bandotan dengan dosis 12 mg/gBB, 24 mg/gBB, 48 mg/gBB, dan satu kelompok sebagai control diberi suspensi Na-CMC 1% b/v. Pemberian ekstrak bandotan dilakukan selama 14 hari dan hari 15 dilakukan pembedahan hewan uji mencit lalu di lihat hasil preparatnya. Berdasarkan hasil penelitian Pengaruh Ekstrak Metanol Herba Bandotan (Ageratum conyzoides L) Terhadap Gambaran Histologi Hati Mencit (Mus musculus) dapat simpulkan bahwa Ekstrak Metanol Herba Bandotan (Ageratum conyzoides L) kelompok perlakuan dengan dosis 12 mg/gBB dan 24 mg/gBB dan 48 mg/gBB menunjukkan adanya Nekrosis, Degenerasi lemak, dan Radang Sedangkan pada kontrol negatif (-) pada pemberian NaCMC mengalami kerusakan degenerasi lemak pada organ hati.