Faktor Risiko Kejadian Kardiomiopati Peripartum di RSUP Dr. M. Djamil Padang: Studi Kasus-Kontrol
Abstract
Kardiomiopati peripartum (peripartum cardiomyopathy/PPCM) merupakan bentuk kardiomiopati yang terjadi pada akhir kehamilan atau periode pascapersalinan dan dapat menyebabkan komplikasi kardiovaskular serius. Identifikasi faktor-faktor yang berhubungan dengan kondisi ini penting untuk mendukung deteksi dini dan meningkatkan kewaspadaan klinis. Penelitian ini brtujuan untuk menganalisis faktor-faktor yang berhubungan dengan kejadian PPCM pada ibu di RSUP Dr. M. Djamil Padang. Penelitian kuantitatif analitik observasional dengan desain kasus-kontrol retrospektif ini melibatkan 80 subjek, terdiri atas 40 kasus PPCM dan 40 kontrol. Data rekam medis dianalisis menggunakan regresi logistik univariat, bivariat, dan multivariat. Hasil penelitian menemukan preeklamsia/eklamsia berhubungan dengan PPCM (aOR = 4,44; 95% CI: 1,67–11,81; p = 0,003). Usia maternal di atas 30 tahun tidak menunjukkan hubungan yang bermakna dengan PPCM (p = 0,609), sedangkan paritas juga tidak menunjukkan hubungan yang bermakna secara statistik (p = 0,082). Model memiliki nilai AUC sebesar 0,737, yang menunjukkan kemampuan diskriminasi sedang. Preeklamsia/eklamsia merupakan faktor yang paling konsisten berhubungan dengan PPCM. Temuan ini perlu ditafsirkan secara hati-hati dengan mempertimbangkan desain retrospektif dan jumlah sampel yang terbatas. Validasi lebih lanjut pada populasi lain diperlukan sebelum model dapat diterapkan dalam praktik klinis.
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